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How was vitamin C discovered?

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Author : Ada
Update time : 2023-02-13 14:27:50
What is Vitamin C?
Vitamin C is an organic compound, which is chemically named L-(+)- Su 'arabine-type 2,3,4,5,6- pentahydroxy -2- hexenoic acid -4- lactone, also known as L- ascorbic acid, with a molecular formula of C6H8O6 and a molecular weight of 176.12. Vitamin C is an organic compound with the chemical name L-(+)- Su 'arabine-type 2, 3, 4, 5, 6- pentahydroxy -2- hexenoic acid -4- lactone, also known as L- ascorbic acid. Its molecular formula is C6H8O6, and its molecular weight is 176.12.
Brief history of research on of Vitamin C
More than 1500 BC, Erbers's medical books in ancient Egypt first recorded diseases very similar to scurvy. According to textual research, a disease recorded in the works of the ancient Greek philosopher Hippocrates is also scurvy. Because people's understanding of the disease was limited at that time, people classified the disease as a plague.
At the end of the 16th century and the beginning of the 17th century, when imperialism was opening up colonies, Holland and Spain sent a large number of ships overseas, and tens of thousands of sailors died in the ocean due to a lack of vitamin C every year. Once, a Spanish sailboat floated on the sea, and people went to find 25 people on board, all of whom died of scurvy. Later, when the crew of another fleet was on the verge of death, they floated to an island by Indians and were saved from death by the Indians with leaf juice. Only then did they begin to realize the close relationship between vitamins and the human body, which aroused widespread concern.
In the early 19th century, the British Navy began to stipulate that every sailor must be rationed with lemon juice every day. In 1911, Funk of Poland put forward his "vitamin hypothesis" in a series of studies on anti-beriberi substances and named the substance he extracted "Vitamines." In 1920, Drummon unified the name of Vitamin and named it "vitamin" (with the tail letter E removed).
In 1922, Szentgyorgy went to work in the Netherlands and began to study the oxidative discoloration of fruits (for example, the surface of apples will turn yellow-brown after being cut). He found that cabbage contains a substance that can prevent this yellowing, and it also contains a similar substance in the adrenal gland of animals, so he studied how to extract this substance from the adrenal gland of fruits and animals. In 1927, Szentgyorgy was invited to work in the laboratory of Frederick Gowland Hopkins, a chemist in London, England. There, he was busy extracting this substance from animal and plant tissues. Because the contents of oranges, lemons, and cabbages are too low, and the bovine adrenal gland with a slightly higher content is not easy to obtain, it was not until 1928 that he successfully extracted a very small amount of this substance, and he obtained the chemical empirical formula C6H8O6 through experiments. At first, he didn't know that this substance was vitamin C, named L-ascorbic acid.
In 1929, Szentgyorgy went to Mayo Hospital in the United States for research. A nearby slaughterhouse provided him with a large number of bovine accessory kidneys for free, from which he separated more Vitamin C, but only 25 grams. He sent half of it to Walter H. Haworth, a British sugar chemist, for analysis. Unfortunately, the technology was not mature at that time, and Haworth could not determine its structure.
In 1930, when Szentgyorgy returned to Hungary, he found that a local pepper contained a lot of hex uronic acids. He finally succeeded in separating 1 kg of pure caproic acid from pepper and sending another batch to Haworth for analysis. Haworth finally determined the correct chemical structure of vitamin C. Later, Tillmans, Vedder, and Harris also extracted vitamin C from various foods. In 1933, vitamin C began to be synthesized artificially.
In 1937, Szentgyorgy won the Nobel Prize in Physiology or Medicine for his research on vitamin C and oxidation reactions in the human body.
Price of Vitamin C
Vitamin C particle size and purity will affect the product's price, and the purchase volume can also affect the cost of Vitamin C. A large amount of large amount will be lower. The price of Vitamin C can be found on our company's official website.
Vitamin C supplier
Luoyang Tongrun Nano Technology Co. Ltd.  (TRUNNANO) Luoyang City, Henan Province, China, is a reliable and high-quality global chemical material supplier and manufacturer. It has more than 12 years of experience providing ultra-high quality chemicals and nanotechnology materials, including Vitamin C, nitride powder, Vitamin C, sulfide powder, and 3D printing powder. If you are looking for high-quality and cost-effective Vitamin C, you are welcome to contact us or inquire any time.
 
 
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