By lql | 12 February 2023 | 0 Comments
What kinds of colloidal gold are there?
What is Colloidal gold?
Colloidal solution refers to a solution formed by dispersing solid particles of drugs or polymer compounds of a certain size in a solvent. The particles of its dispersion system are generally between 1 and 100 nanometers, most of the dispersion media are water, and a few are non-aqueous solvents. Solid particles are dispersed in the solvent as multi-molecular aggregates (colloidal particles), forming a heterogeneous dispersion system (lyophobic glue). Polymer compounds are dispersed in the solvent as single molecules, forming a single-phase homogeneous dispersion system (lyophilic glue). This kind of solution has its own unique properties, which are different from both low molecular dispersion system-true solution (dispersed phase particle is less than 1 nm) and coarse dispersion system-suspension (dispersed phase particle is more than 100 nm). A colloidal solution is widely used in pharmacy, especially in the preparation of animal and plant drugs.
Colloidal solution refers to a solution formed by dispersing solid particles of drugs or polymer compounds of a certain size in a solvent. The particles of its dispersion system are generally between 1 and 100 nanometers, most of the dispersion media are water, and a few are non-aqueous solvents. Solid particles are dispersed in the solvent as multi-molecular aggregates (colloidal particles), forming a heterogeneous dispersion system (lyophobic glue). Polymer compounds are dispersed in the solvent as single molecules, forming a single-phase homogeneous dispersion system (lyophilic glue). This kind of solution has its own unique properties, which are different from both low molecular dispersion system-true solution (dispersed phase particle is less than 1 nm) and coarse dispersion system-suspension (dispersed phase particle is more than 100 nm). A colloidal solution is widely used in pharmacy, especially in the preparation of animal and plant drugs.
Classifications of Colloidal gold
Colloids can be divided into lyophilic colloids and lyophobic colloids according to the affinity between colloidal particles and the dispersion medium. When the dispersion medium is water, they are called hydrophilic colloids and hydrophobic colloids. The system formed by colloid dispersed in a dispersion medium is called a colloidal solution, and the colloidal aqueous solution is widely used in traditional Chinese medicine pharmacy.
Hydrophilic colloid solution
Colloidal compounds (protein and other polymer compounds) contain many hydrophilic groups in their molecular structures, which can interact with water molecules. After hydration, the particles are dispersed in water in a molecular state to form a hydrophilic colloid solution. For example, animal glue (such as collar corgi asini, colla Cornus Cervi, gelatin, and bone glue), aqueous solutions of enzymes (such as pepsin, trypsin, lysozyme, and urokinase), and other biochemical preparations containing protein, cellulose derivatives in plants, natural polysaccharides, mucilages and gums, and colloidal solutions formed by synthetic dextran and polyvinylpyrrolidone after contact with water all belong to this category. The vast majority of hydrocolloids are polymer compounds, so hydrocolloid solution is also called polymer aqueous solution. With the increase of the number of nonpolar genes, the hydrophilicity of colloids decreases, while the affinity for semi-polar solvents and nonpolar solvents increases. When colloidal particles are dispersed in these solvents, the solution formed is called lyophilic colloid solution or polymer non-aqueous solution, such as zein ethanol solution or acetone solution.
Hydrophobic colloidal solution
The hydrophobic colloidal solution, also known as sol, is a dispersion system formed by dispersing particles (1 ~ 100 nm) aggregated by multiple molecules in water. The hydration between particles and water is very weak, so there is an obvious interface between them and water, so the sol is a micro-multiphase dispersion system with coalescence instability. There is a thin electric double-layer structure on the surface of soil particles, which contributes to the stability of sol. There are few hydrophobic colloids in pharmaceutical dosage forms, but they are often encountered in the preparation of traditional Chinese medicine. For example, in the preparation of adhesive, a small amount of alum is added to the adhesive to precipitate and remove fine solid particles (impurities such as dust with a particle size of 1-100 nm) in the adhesive.
Protective colloid solution
As mentioned above, the hydrophobic colloidal solution has the instability that colloidal particles are easy to aggregate into large particles, resulting in precipitation. A certain amount of hydrocolloid solution is added to the hydrophobic colloid solution so that a layer of hydrocolloid is adsorbed on the surface of colloidal particles, which hinders the mutual contact between colloidal particles and increases the stability of hydrophobic colloid. This effect is called the protective effect of colloid and this kind of colloid is called protective colloid. From this point of view, solid particles can absorb some glue, so they can also be regarded as protective colloids; Any Chinese medicine decoction containing gelatin (such as collar corgi asini, colla Cornus Cervi, etc.) may produce a protective colloid when the gelatin is melted into the soup so that the components with poor water solubility are dispersed in the soup, which is beneficial to the drug effect.
Gel and dry glue
Some hydrocolloid solutions, such as gelatin water solution, donkey-hide gelatin, antler glue, other water solutions, agar water solution, etc., are viscous flowing liquids under warm conditions. However, when the temperature decreases, the polymer dispersed in the chain forms a network structure, and the dispersion medium water is completely contained in the network structure, forming a non-flowing semi-solid object called gel, and the process of forming gel is called gelation. 2% gelatin aqueous solution can form a gel at a certain temperature; However, aqueous solutions such as donkey-hide gelatin need a large concentration to form gel because part of collagen is hydrolyzed. When the gel is placed at a proper temperature, it loses the moisture in the network structure and forms a glue stick block, which is called xerogel. The dry gel can be dissolved in water to form a hydrophilic colloid solution. If the dry gel is crushed, it will dissolve quickly and form a hydrophilic colloid solution quickly in warm water. In the whole process of preparation and application of traditional Chinese medicine glue, collagen or denatured products are actually dissolved in water to form a hydrophilic colloid solution; Concentrated to a certain concentration, and cooled to form a gel; Cut the gel into pieces and air dry to make it into the dry gel.
Thixotropic glue solution
A few colloidal solutions, such as aluminum stearate dispersed in vegetable oil, gradually become semi-solid gel when standing at a certain temperature and then become flowable colloidal solutions when shaking. This property of the colloidal solution is called thixotropy, and this colloid is called thixotropic glue. The thixotropic gel is sometimes encountered in suspension eye drops or injections.
Price of Colloidal gold
Colloidal gold particle size and purity will affect the product's price, and the purchase volume can also affect the cost of Colloidal gold. A large amount of large amount will be lower. The price of Colloidal gold can be found on our company's official website.
Colloidal gold supplier
Luoyang Tongrun Nano Technology Co. Ltd. (TRUNNANO) Luoyang City, Henan Province, China, is a reliable and high-quality global chemical material supplier and manufacturer. It has more than 12 years of experience providing ultra-high quality chemicals and nanotechnology materials, including Colloidal gold, nitride powder, Colloidal gold, sulfide powder, and 3D printing powder. If you are looking for high-quality and cost-effective Colloidal gold, you are welcome to contact us or inquire any time.
Colloids can be divided into lyophilic colloids and lyophobic colloids according to the affinity between colloidal particles and the dispersion medium. When the dispersion medium is water, they are called hydrophilic colloids and hydrophobic colloids. The system formed by colloid dispersed in a dispersion medium is called a colloidal solution, and the colloidal aqueous solution is widely used in traditional Chinese medicine pharmacy.
Hydrophilic colloid solution
Colloidal compounds (protein and other polymer compounds) contain many hydrophilic groups in their molecular structures, which can interact with water molecules. After hydration, the particles are dispersed in water in a molecular state to form a hydrophilic colloid solution. For example, animal glue (such as collar corgi asini, colla Cornus Cervi, gelatin, and bone glue), aqueous solutions of enzymes (such as pepsin, trypsin, lysozyme, and urokinase), and other biochemical preparations containing protein, cellulose derivatives in plants, natural polysaccharides, mucilages and gums, and colloidal solutions formed by synthetic dextran and polyvinylpyrrolidone after contact with water all belong to this category. The vast majority of hydrocolloids are polymer compounds, so hydrocolloid solution is also called polymer aqueous solution. With the increase of the number of nonpolar genes, the hydrophilicity of colloids decreases, while the affinity for semi-polar solvents and nonpolar solvents increases. When colloidal particles are dispersed in these solvents, the solution formed is called lyophilic colloid solution or polymer non-aqueous solution, such as zein ethanol solution or acetone solution.
Hydrophobic colloidal solution
The hydrophobic colloidal solution, also known as sol, is a dispersion system formed by dispersing particles (1 ~ 100 nm) aggregated by multiple molecules in water. The hydration between particles and water is very weak, so there is an obvious interface between them and water, so the sol is a micro-multiphase dispersion system with coalescence instability. There is a thin electric double-layer structure on the surface of soil particles, which contributes to the stability of sol. There are few hydrophobic colloids in pharmaceutical dosage forms, but they are often encountered in the preparation of traditional Chinese medicine. For example, in the preparation of adhesive, a small amount of alum is added to the adhesive to precipitate and remove fine solid particles (impurities such as dust with a particle size of 1-100 nm) in the adhesive.
Protective colloid solution
As mentioned above, the hydrophobic colloidal solution has the instability that colloidal particles are easy to aggregate into large particles, resulting in precipitation. A certain amount of hydrocolloid solution is added to the hydrophobic colloid solution so that a layer of hydrocolloid is adsorbed on the surface of colloidal particles, which hinders the mutual contact between colloidal particles and increases the stability of hydrophobic colloid. This effect is called the protective effect of colloid and this kind of colloid is called protective colloid. From this point of view, solid particles can absorb some glue, so they can also be regarded as protective colloids; Any Chinese medicine decoction containing gelatin (such as collar corgi asini, colla Cornus Cervi, etc.) may produce a protective colloid when the gelatin is melted into the soup so that the components with poor water solubility are dispersed in the soup, which is beneficial to the drug effect.
Gel and dry glue
Some hydrocolloid solutions, such as gelatin water solution, donkey-hide gelatin, antler glue, other water solutions, agar water solution, etc., are viscous flowing liquids under warm conditions. However, when the temperature decreases, the polymer dispersed in the chain forms a network structure, and the dispersion medium water is completely contained in the network structure, forming a non-flowing semi-solid object called gel, and the process of forming gel is called gelation. 2% gelatin aqueous solution can form a gel at a certain temperature; However, aqueous solutions such as donkey-hide gelatin need a large concentration to form gel because part of collagen is hydrolyzed. When the gel is placed at a proper temperature, it loses the moisture in the network structure and forms a glue stick block, which is called xerogel. The dry gel can be dissolved in water to form a hydrophilic colloid solution. If the dry gel is crushed, it will dissolve quickly and form a hydrophilic colloid solution quickly in warm water. In the whole process of preparation and application of traditional Chinese medicine glue, collagen or denatured products are actually dissolved in water to form a hydrophilic colloid solution; Concentrated to a certain concentration, and cooled to form a gel; Cut the gel into pieces and air dry to make it into the dry gel.
Thixotropic glue solution
A few colloidal solutions, such as aluminum stearate dispersed in vegetable oil, gradually become semi-solid gel when standing at a certain temperature and then become flowable colloidal solutions when shaking. This property of the colloidal solution is called thixotropy, and this colloid is called thixotropic glue. The thixotropic gel is sometimes encountered in suspension eye drops or injections.
Price of Colloidal gold
Colloidal gold particle size and purity will affect the product's price, and the purchase volume can also affect the cost of Colloidal gold. A large amount of large amount will be lower. The price of Colloidal gold can be found on our company's official website.
Colloidal gold supplier
Luoyang Tongrun Nano Technology Co. Ltd. (TRUNNANO) Luoyang City, Henan Province, China, is a reliable and high-quality global chemical material supplier and manufacturer. It has more than 12 years of experience providing ultra-high quality chemicals and nanotechnology materials, including Colloidal gold, nitride powder, Colloidal gold, sulfide powder, and 3D printing powder. If you are looking for high-quality and cost-effective Colloidal gold, you are welcome to contact us or inquire any time.
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